What Is Biochemical Recurrence After Prostate Cancer? PSA Rise, Definitions and Next Steps
PSA • signalSurgery • ≥0.2Radiation • nadir+2Kinetics • riskImaging • salvage Biochemical recurrence means prostate-specific antigen (PSA) has risen after treatment intended to control or cure prostate cancer, suggesting recurrent cancer before recurrence is necessarily visible on imaging or causing symptoms. It is also called biochemical relapse or PSA recurrence. The definition depends on the […]
Prostate Cancer Recurrence: Local, Biochemical and Metastatic Recurrence
PSA • biochemicalBed • localNodes • regionalBone • distantHormone • state Prostate cancer recurrence means cancer has returned or persisted after treatment intended to control the original disease. Recurrence may first appear only as a PSA rise, may be confined to the prostate or prostate bed, may involve pelvic lymph nodes, or may be metastatic […]
Where Is the Prostate Located? Relation to the Bladder, Urethra and Rectum
Prostate anatomy · Evidence-based patient education · Updated August 26, 2026 Where Is the Prostate Located? Relation to the Bladder, Urethra and Rectum The prostate is a gland in the lower male pelvis. Its position at the junction of the urinary and reproductive tracts explains why prostate enlargement can affect urination, why part of the […]
What Is the Prostate Gland? Anatomy, Function and Role in Male Reproduction
The prostate gland is a male reproductive organ located below the bladder and in front of the rectum. It surrounds the proximal urethra, produces fluid that becomes part of semen and contracts during ejaculation. Its location connects reproductive function with the lower urinary tract. Prostate tissue does not store urine or produce sperm. It supports […]
What Are the Zones of the Prostate? Peripheral, Transition and Central Anatomy
Prostate anatomy · Zonal model · Updated August 26, 2026 What Are the Zones of the Prostate? Peripheral, Transition and Central Anatomy The prostate is organized into regions with different positions, tissue composition and disease patterns. Understanding those regions explains why benign enlargement commonly develops around the urethra while many prostate cancers arise farther back, […]
What Is the Prostate Transition Zone? Anatomy, BPH Growth and Clinical Significance
Prostate anatomy · BPH growth · Updated August 26, 2026 What Is the Prostate Transition Zone? Anatomy, BPH Growth and Clinical Significance The transition zone is a small inner region of the prostate with outsized clinical importance. Its position around the urethra explains why tissue growth there can alter urine flow, while its mixed glandular […]
What Is the Prostate Peripheral Zone? Anatomy and Prostate Cancer Relevance
Prostate anatomy · MRI and cancer context · Updated August 26, 2026 What Is the Prostate Peripheral Zone? Anatomy and Prostate Cancer Relevance The peripheral zone is the largest glandular region of the prostate and occupies most of its posterior and lateral outer tissue. Its proximity to the rectum makes part of it palpable, and […]
What Is the Prostatic Urethra? Location, Function and Bladder Outlet Obstruction
Prostate anatomy · Urinary and ejaculatory pathway · Updated August 26, 2026 What Is the Prostatic Urethra? Location, Function and Bladder Outlet Obstruction The prostatic urethra is the section of the male urethra that passes through the prostate. It is simultaneously a urine conduit, the receiving channel for prostate and ejaculatory-duct secretions, and the segment […]
What Is the Prostate Capsule? Anatomy, Boundaries and Clinical Significance
Prostate anatomy · MRI, pathology and surgery · Updated August 26, 2026 What Is the Prostate Capsule? Anatomy, Boundaries and Clinical Significance The term prostate capsule suggests a complete, peelable shell. Human anatomy is less tidy. The prostate’s edge is formed by a variable condensation of fibromuscular stroma that merges with tissue inside the gland […]
What Are the Seminal Vesicles? Anatomy, Seminal Fluid and Ejaculatory Function
Accessory gland anatomy · Fertility · Prostate-cancer staging What Are the Seminal Vesicles? Anatomy, Seminal Fluid and Ejaculatory Function The seminal vesicles are paired glands tucked behind the bladder and above the prostate. Despite their name, they do not store sperm. Their highly folded lining produces most of the fluid in a typical ejaculate, including […]